DNA strand exchange and hydrophobic interactions between biomolecules

نویسنده

  • BOBO FENG
چکیده

2015 Ungefär 100 kilo ATP syntetiseras i kroppen varje dag av ATP-syntas, ett sammansatt proteinkomplex med tre aktiva centra. Komplexet sitter förankrat i ett biologiskt membran med hjälp av hydrofob attraktion och består av en roterande och en statisk del. En ATP-molekyl syntetiseras per tredjedels varv. Trots att varje aktivt centrum skulle kunna fungera oberoende av de andra, sparas mycket energi av att de enskilda reaktionerna fördelas jämnt över tiden. I artikel 6 i denna avhandling kallar vi detta fenomen för ”katalys genom fasförskjutning”.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evidence for hydrophobic catalysis of DNA strand exchange.

The catalytic role of hydrophobic co-solutes in DNA strand exchange is demonstrated by FRET kinetics. Two mechanisms that contribute to this are base stacking destabilisation and nucleation-promoted DNA strand invasion. We propose that hydrophobic catalysis is involved in the strand-exchange activity of recombination enzymes.

متن کامل

DNA strand exchange catalyzed by molecular crowding in PEG solutions.

DNA strand exchange is catalyzed by molecular crowding and hydrophobic interactions in concentrated aqueous solutions of polyethylene glycol, a discovery of relevance for understanding the function of recombination enzymes and with potential applications to DNA nanotechnology.

متن کامل

Investigation of Solvent Effects on Interaction of Single-Strand DNA with Open-End of Single Walled Carbon Nanotubes Using QM and MM methods

The interaction of biomolecules with carbon nanotubes (CNTs) has generated a great deal ofinterest in the past few years. The interaction between B-form single-strand DNA (ssDNA) andsingle-walled carbon nanotubes (SWCNTs) is a subject of intense current interest; however thereare a relatively small number of papers in the literature dealing with interaction of DNA andSWCNTs. In this work we inv...

متن کامل

Simulation study of the performance of a biologically sensitive field effect transistor

The transformation of biochemical information into a physical or chemical signal is the basic idea behind a biosensor. The efficient detection of charged biomolecules by biosensor with appropriate device has caught tremendous research interest in the present decade. The present work is related to the simulation study of the performance of a functionalized surface of a biologically sensitive fie...

متن کامل

Simulation study of the performance of a biologically sensitive field effect transistor

The transformation of biochemical information into a physical or chemical signal is the basic idea behind a biosensor. The efficient detection of charged biomolecules by biosensor with appropriate device has caught tremendous research interest in the present decade. The present work is related to the simulation study of the performance of a functionalized surface of a biologically sensitive fie...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2015